2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate (CAS 122111-11-9) - Fluorinated Sugar Intermediate - Kohima

2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate (CAS: 122111-11-9) is a highly specialized organic compound featuring a uniquely functionalized tetrahydrofuran core. Its molecular structure is distinguished by the presence of difluoro substitution, benzoyloxy protecting groups, and a methanesulfonyl moiety, which together confer high synthetic value and controlled reactivity.

In chemical synthesis, this compound is primarily used as an advanced building block for the construction of structurally complex molecules. The difluorinated sugar framework is particularly valuable in fluorine chemistry, where fluorine incorporation is known to influence molecular stability, lipophilicity, and metabolic behavior. The methanesulfonate group serves as an excellent leaving group, enabling further functionalization through substitution reactions.

From a biological research perspective, 2-Deoxy-2,2-difluoro-D-erythro-pentofuranose derivatives are investigated as biochemical probes for studying enzyme mechanisms, especially those involving carbohydrate-processing enzymes. The strategic placement of fluorine atoms allows researchers to modulate enzymatic interactions while maintaining close structural similarity to native substrates.

In medicinal and pharmaceutical research, this compound has attracted interest as a synthetic intermediate for fluorinated bioactive molecules. Fluorinated sugar analogs are frequently explored for their potential anti-inflammatory and anticancer properties, as well as for improving the pharmacokinetic profiles of drug candidates. The protected functional groups in this molecule support selective transformations during multistep synthesis routes.

Industrial applications extend to the development of advanced pharmaceutical intermediates and specialty materials, where precise molecular design and functional group control are critical. Its structural complexity and versatility make it suitable for use in high-value research, development, and manufacturing processes.

Overall,2-Deoxy-2,2-difluoro-D-erythro-pentofuranose-3,5-dibenzoate-1-methanesulfonate (CAS: 122111-11-9) represents a valuable fluorinated intermediate for chemical synthesis, biochemical research, and pharmaceutical innovation.