2-Methylindole-3-acetic Acid CAS 1912-43-2 - Indole Derivative for Plant Science and Organic Synthesis - Katni

2-Methylindole-3-acetic acid CAS:1912-43-2 is an indole derivative featuring a methyl substituent at the 2-position and an acetic acid group at the 3-position of the indole ring. With its distinctive heterocyclic structure and carboxylic acid functionality, this compound is of interest in plant science, pharmaceutical research, and synthetic organic chemistry.

The compound has a molecular formula of C11H11NO2 and a molecular weight of 189.21 g/mol. Its structural features make it a useful research compound and a building block for preparing a range of functional indole derivatives.

Applications of 2-Methylindole-3-acetic Acid
1. Plant Science and Growth-Regulation Research
Indole-based compounds are widely studied in plant science because of their relevance to plant growth and development. 2-Methylindole-3-acetic acid is associated with plant growth regulator research and can serve as a compound of interest in studies involving indole derivatives and plant-related biological activity.

Its structural relationship to indole acetic acid compounds makes it relevant to research exploring the chemical diversity and biological functions of substituted indoles.

2. Synthesis of Indole-Based Pharmaceutical Compounds
2-Methylindole-3-acetic acid can be used as a reactant in the preparation of N-methyl-N-[[(nitrophenyl)sulfonyl]oxy]indoleacetamide derivatives. These compounds provide examples of how substituted indole structures can be further modified for medicinal chemistry research.

It is also used in the preparation of indomethacin analogs and related derivatives, supporting research into structurally diverse indole-based compounds.

3. Organic Synthesis and Coupling Reactions
The carboxylic acid functionality of 2-Methylindole-3-acetic acid provides a useful site for chemical transformation. The compound can participate in coupling reactions with diazomethane, making it relevant to synthetic studies involving the modification of carboxylic acid groups.

4. Research on Biologically Active Heterocycles
2-Methylindole-3-acetic acid can serve as a reactant in the synthesis of (methylindolyl)methyltriazolethiones and (methylindolyl)methylthiadiazolylamines. These classes of compounds have been investigated as potential antidepressant and anticonvulsant agents.

Such synthetic applications demonstrate the value of substituted indole building blocks in medicinal chemistry and the exploration of new heterocyclic structures.

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