5-Bromopyrimidine (CAS: 4595-59-9): A Key Intermediate for Pharmaceutical and Agrochemical Synthesis - Bhubaneswar

5-Bromopyrimidine (CAS Number: 4595-59-9) is a halogenated heterocyclic compound that serves as a valuable intermediate in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. As a brominated derivative of pyrimidine, it offers high reactivity at the 5-position, making it a preferred substrate for metal-catalyzed cross-coupling reactions such as Suzuki, Heck, and Buchwald–Hartwig.

Basic Information

Chemical Name: 5-Bromopyrimidine

CAS Number: 4595-59-9

Molecular Formula: C4H3BrN2

Molecular Weight: 158.98 g/mol

Appearance: off-white crystal powder

Purity: ≥98% (GC or HPLC)

Applications

5-Bromopyrimidine is widely used in the preparation of:

l Pharmaceutical APIs – as a key intermediate in antiviral, anticancer, and kinase inhibitor compounds.

l Agrochemicals – for the synthesis of herbicidal and fungicidal actives.

l Advanced materials – as a precursor for functionalized pyrimidine-based ligands and bioactive heterocycles.

Due to the electron-deficient nature of the pyrimidine ring, the bromine atom at position 5 readily undergoes substitution or palladium-catalyzed coupling, enabling the construction of diverse molecular scaffolds.

Market & Supply

As demand for nitrogen-containing heterocycles continues to grow in pharmaceutical R&D, 5-Bromopyrimidine has gained increasing importance. UCHEM supplies high-purity 5-Bromopyrimidine with full documentation (COA, MSDS, NMR) and supports global delivery.

We also supply the following products?

2-Chloropyrimidine CAS:1722-12-9

2-Bromopyrimidine CAS:4595-60-2

2-Cyanopyrimidine CAS:14080-23-0

Contact Us

For bulk inquiries, technical specifications, or sample requests of 5-Bromopyrimidine (CAS 4595-59-9), please contact UCHEM at www.myuchem.com or email uchemsales@gmail.com.