Ethyl 3-hydroxybenzoate (CAS 7781-98-8): Properties, Applications, and Research Value - Anand

Ethyl 3-hydroxybenzoate (CAS 7781-98-8) is an aromatic ester derived from 3-hydroxybenzoic acid and ethanol. It appears as a white to off-white crystalline solid or powder and is valued for its stable chemical structure, moderate lipophilicity, and versatile reactivity. Owing to the presence of both a phenolic hydroxyl group and an ester functionality, this compound serves as an important intermediate in fine chemical synthesis and research applications.

In organic synthesis, ethyl 3-hydroxybenzoate is widely used as a building block for the preparation of more complex aromatic compounds. The phenolic –OH group allows for further functionalization through etherification, esterification, or coupling reactions, while the ester moiety can undergo hydrolysis or transesterification. These features make it a useful precursor in the synthesis of pharmaceuticals, agrochemicals, and specialty intermediates.

In the pharmaceutical and life science fields, ethyl 3-hydroxybenzoate is commonly employed as an intermediate in drug discovery and medicinal chemistry research. Compounds derived from hydroxybenzoates are studied for their potential antimicrobial, antioxidant, and anti-inflammatory activities. As a result, this compound is often used in structure–activity relationship (SAR) studies and early-stage research projects.

In materials science and industrial chemistry, ethyl 3-hydroxybenzoate can be used in the development of functional additives, specialty polymers, and fragrance or flavor intermediates. Its aromatic structure contributes to thermal stability, while its ester functionality improves compatibility with organic matrices, making it useful in formulation research.

From a research and supply standpoint, ethyl 3-hydroxybenzoate is appreciated for its good stability, ease of handling, and reproducible performance in laboratory and pilot-scale reactions. UCHEM can supply ethyl 3-hydroxybenzoate (CAS 7781-98-8) with consistent quality, suitable for R&D, method development, and industrial application needs.

Overall, ethyl 3-hydroxybenzoate is a versatile and reliable aromatic ester that plays an important role in organic synthesis, pharmaceutical research, and materials development, making it a valuable compound across multiple scientific and industrial sectors.